Endocrine Abstracts

Introduction: Thyrotropin-secreting pituitary adenomas (TSHomas) are a rare cause of hyperthyroidism and represent <1% of all pituitary adenomas. The majority of TSHomas (70%) secrete TSH alone, while mixed adenomas are not infrequent.Design: Herein, we reported the findings of six patients with TSHoma (mean age 44 yr, 4 female, 2 male). Mean TSH value was 15.1 mIU/L (3.3–38.0) who were followed-up in our department.Result...

Clinical spectrum of phaeochromocytoma syndromes are very heterogeneous. Sometimes life threatening hypertensive attacks may be the presenting symptom or the clinical picture may be subtle that a nonspecific symptom like fatigue can lead to diagnosis. We herein present two phaeochromocytoma cases with distinct clinical features.Case 1: A 20-year-old female patient admitted to emergency department with blurred vision and headache. She experienced headache...

Oncogenic osteomalacia is a rare paraneoplastic syndrome, which can be associated with phosphaturic mesenchymal tumor or non-mesenchymal tumour. This tumour produces fibroblast growth factor 23 (FGF-23) that leads to subsequent hypophosphataemic osteomalacia. We, hereby present a patient with oncogenic osteomalasia who is misdiagnosed as ankylosing spondylitis. A 54-year old man with weakness, severe arthralgia involving pelvis, hip joints and lower extremities referred to the...

Introduction: Differentiated thyroid cancer accounts for 1.5% of all pediatric malignancies. Papillary thyroid cancer (PTC) is the most common subtype and is associated with more advanced disease at diagnosis compared to adults. The aim of this study was to identify long-term outcomes of pediatric PTC.Methods: Records of 30 patients with PTC diagnosed in childhood and adolescence and followed up at Istanbul Faculty of Medicine were reviewed retrospective...

Aim: To determine the prevalence of impulse control disorder (ICD) in patients with Cushing’s disease (CD) treated with cabergoline (CBG) compared to CBG-naive patients with CD.Methods: We performed a cross-sectional study in patients with CD followed at 5 referral centers based in Istanbul. Eligible patients with CD were those with current CBG treatment for ≥ 3 months. Eligible controls were CBG-naive patients with CD that were matched for ag...

Backgrounds and aims: We aimed to determine final status of carbohydrate (CHO) intolerance of women with GDM who were followed between 3 months and 10 years after delivery.Materials and methods: Two hundred and fourty participants with GDM history were enrolled into study and divided into two groups. [Group I: 40 women (38.0±6.3 years) who had delivery before 11±2 years ago, Group II: 200 women (34.0±5.1 years) who had delivery within 3&#1...

Introduction: Isolated bone metastasis of endometrium carcinoma is rare; but if it occurs, pelvis and vertebrae are involved mostly. Co-existence of undiagnosed Paget’s disease in a patient with malignancy causes major problems in differential diagnosis.Case: A 77 year-old woman was admitted to our hospital with severe pelvic pain. She had been diagnosed with inoperable endometrium adenocarcinoma for over a year. Metastatic bone disease was suspecte...

Background: Adrenal incidentaloma (AI) is described as an adrenal mass detected on imaging not performed for adrenal disease. In coronavirus disease 2019 (COVID-19) pandemic, chest CT evaluation was performed for all ages in adults. In this study, we aimed to detect adrenal adenoma(s) which were identified with chest CT, during COVID-19 diagnostic work-up to find AI prevalence in our population.Methods: All patients who underwent chest CT examination for...

Objective: Transgender individuals endure gender dysphoria and incongruence between physical appearance and gender identity. We aimed to investigate effects of gender affirming treatments on sex hormone levels, mental well being and body image quality of life in these individuals. Material and Method: This is a descriptive cross sectional study. Transgender individuals who were transitioned from pediatric to adult care (n: 12) and who were formerly follo...

Introduction: Effective management of the transition from childhood to adulthood in congenital adrenal hyperplasia (CAH) can reduce the problems that may arise in the follow-up during adulthood.Aim: Evaluation of the clinical characteristics and sociodemographic data of CAH patients transferred from the Pediatric Endocrinology Clinic to the Adult department of our hospital and the comparison of the 2 transition models carried out during this period was t...